Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation

<p>Abstract</p> <p>Background</p> <p>We have previously reported significant downregulation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in prostate cancer (PCa) compared to the surrounding benign tissue. UCHL1 plays an important role in ubiquitin system and diffe...

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Bibliographic Details
Main Authors: Meyer-Schwesinger Catherine, Sültmann Holger, Bokemeyer Carsten, Senff Tina, Sauter Guido, Schlomm Thorsten, Barett Christine, Mundt Frederike, Lohmann Frithjof, Braig Melanie, Jost Edgar, Ummanni Ramesh, Brümmendorf Tim H, Balabanov Stefan
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Molecular Cancer
Subjects:
prostate cancer
UCHL1
ubiquitin system
tumour suppression
signalling
Online Access:http://www.molecular-cancer.com/content/10/1/129

Internet

http://www.molecular-cancer.com/content/10/1/129

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