Role of Uric Acid in Vascular Remodeling: Cytoskeleton Changes and Migration in VSMCs

The mechanisms by which hyperuricemia induces vascular dysfunction and contributes to cardiovascular disease are still debated. Phenotypic transition is a property of vascular smooth muscle cells (VSMCs) involved in organ damage. The aim of this study was to investigate the effects of uric acid (UA)...

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Bibliographic Details
Main Authors: Elisa Russo, Maria Bertolotto, Valentina Zanetti, Daniela Picciotto, Pasquale Esposito, Federico Carbone, Fabrizio Montecucco, Roberto Pontremoli, Giacomo Garibotto, Francesca Viazzi, Daniela Verzola
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/3/2960