Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts

Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts

Myotonic dystrophy type 1 (DM1) is a hereditary and multisystemic disease characterized by myotonia, progressive distal muscle weakness and atrophy. The molecular mechanisms underlying this disease are still poorly characterized, although there are some hypotheses that envisage to explain the multis...

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Bibliographic Details
Main Authors: Diana Viegas, Cátia D. Pereira, Filipa Martins, Tiago Mateus, Odete A. B. da Cruz e Silva, Maria Teresa Herdeiro, Sandra Rebelo
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
myotonic dystrophy type 1
nuclear envelope
DMPK
nuclear profile
lamin A/C
emerin
Online Access:https://www.mdpi.com/1422-0067/23/1/522

Internet

https://www.mdpi.com/1422-0067/23/1/522

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