FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice

Summary Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an inherited, progressive and incurable muscle disorder. However, the molecular mechanisms underlying disease pathogenesis are not fully unders...

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Bibliographic Details
Main Authors: Predrag Krajacic, Emidio E. Pistilli, Jessica E. Tanis, Tejvir S. Khurana, S. Todd Lamitina
Format: Article
Language:English
Published: The Company of Biologists 2013-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/11/1245