FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice
Summary Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an inherited, progressive and incurable muscle disorder. However, the molecular mechanisms underlying disease pathogenesis are not fully unders...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-10-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/2/11/1245 |