Characterizing heterogeneity along EMT and metabolic axes in colorectal cancer reveals underlying consensus molecular subtype-specific trends

Characterizing heterogeneity along EMT and metabolic axes in colorectal cancer reveals underlying consensus molecular subtype-specific trends

Colorectal cancer (CRC) is highly heterogeneous with variable survival outcomes and therapeutic vulnerabilities. A commonly used classification system in CRC is the Consensus Molecular Subtypes (CMS) based on gene expression patterns. However, how these CMS categories connect to axes of phenotypic p...

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Bibliographic Details
Main Authors: Manas Sehgal, Soundharya Ramu, Joel Markus Vaz, Yogheshwer Raja Ganapathy, Srinath Muralidharan, Sankalpa Venkatraghavan, Mohit Kumar Jolly
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Translational Oncology
Subjects:
Phenotypic heterogeneity
EMT
Colorectal cancer
Metabolic plasticity
Meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323002310

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http://www.sciencedirect.com/science/article/pii/S1936523323002310

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