The enrichment of the gut microbiota Lachnoclostridium is associated with the presence of intratumoral tertiary lymphoid structures in hepatocellular carcinoma

The enrichment of the gut microbiota Lachnoclostridium is associated with the presence of intratumoral tertiary lymphoid structures in hepatocellular carcinoma

Backgrounds and aimsImmunotherapies have formed an entirely new treatment paradigm for hepatocellular carcinoma (HCC). Tertiary lymphoid structure (TLS) has been associated with good response to immunotherapy in most solid tumors. Nonetheless, the role of TLS in human HCC remains controversial, and...

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Bibliographic Details
Main Authors: Rui Zhao, Jiacheng Li, Bo Chen, Jungang Zhao, Leyin Hu, Kate Huang, Qiwen Chen, Jiangqiao Yao, Ganglian Lin, Lishimeng Bao, Mengmeng Lu, Yi Wang, Gang Chen, Fang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
hepatocellular carcinoma (HCC)
tumor immune microenvironment (TIME)
tertiary lymphoid structure (TLS)
gut microbiota
Lachnoclostridium
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289753/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289753/full

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