Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer’s disease

Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer’s disease

Abstract The deposition of Amyloid-beta peptides (Aβ) is detected at an earlier stage in Alzheimer’s disease (AD) pathology. Thus, the approach toward Aβ metabolism is considered to play a critical role in the onset and progression of AD. Mounting evidence suggests that lifestyle-related diseases ar...

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Main Authors: Yasuha Noda, Akira Kuzuya, Kyousuke Tanigawa, Mitsugu Araki, Ryoko Kawai, Biao Ma, Yoko Sasakura, Masato Maesako, Yoshitaka Tashiro, Masakazu Miyamoto, Kengo Uemura, Yasushi Okuno, Ayae Kinoshita
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Molecular Brain
Online Access:http://link.springer.com/article/10.1186/s13041-018-0401-8

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http://link.springer.com/article/10.1186/s13041-018-0401-8

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