A potential immunotherapy target for breast cancer: parenchymal and immune-stromal expression of the NLRP3 inflammasome pathway

A potential immunotherapy target for breast cancer: parenchymal and immune-stromal expression of the NLRP3 inflammasome pathway

Abstract Background The NOD-, LRR- and pyrin domain‑containing 3 (NLRP3) inflammasome is a critical component of the innate immune system. It has been known to play an important role in the carcinogenesis and prognosis of breast cancer patients. While the clinical evidence of the relationship betwee...

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Bibliographic Details
Main Authors: Qian-mei Zhu, Hui-xian Li, Pei-qing Ma, Lin-xin Wu, Tai-hang Wang, Wen-bin Li, Lin Zhang, Xue Yang, Xiangyi Kong, Yu-lin Sun, Tao Yan
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
NLRP3 inflammasome
Innate immune system
Caspase-1
ASC
Breast cancer
Prognosis
Online Access:https://doi.org/10.1186/s12885-023-11609-4

Internet

https://doi.org/10.1186/s12885-023-11609-4

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