Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC

Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC

Pharmacogenetics plays a key role in personalized cancer treatment. Currently, the clinically available pharmacogenetic markers for metastatic colorectal cancer (mCRC) are in genes related to drug metabolism, such as DPYD for fluoropyrimidines and UGT1A1 for irinotecan. Recently, the impact of host...

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Bibliographic Details
Main Authors: Lucia Scarabel, Alessia Bignucolo, Giuseppe Toffoli, Erika Cecchin, Elena De Mattia
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
colorectal cancer
mCRC
biomarkers
genetic susceptibility factors
immunotherapy
pharmacogenetics
Online Access:https://www.mdpi.com/1999-4923/14/11/2468

Internet

https://www.mdpi.com/1999-4923/14/11/2468

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