An Intestinal Microbiome Intervention Affects Biochemical Disease Activity in Patients with Antiphospholipid Syndrome

Background The origin of autoantibodies in patients with antiphospholipid syndrome (APS) is unknown. The gut microbiome contributes to autoimmunity and contains peptide homologues to the main APS autoantigen, which affect disease activity in animal models. Alteration of the gut microbiota...

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Main Authors: Valérie L. B. I. Jansen, Dagmar J. M. van Mourik, Mark Davids, Kika van Bergen en Henegouwen, Tessa Noordermeer, Johannes H. M. Levels, Maarten Limper, Michiel Coppens, Max Nieuwdorp, Rolf T. Urbanus, Saskia Middeldorp, Thijs E. van Mens
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2024-07-01
Series:TH Open
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788653