Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process.

Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process.

A delicate balance between genome stability and instability ensures genome integrity while generating genetic diversity, a critical step for evolution. Indeed, while excessive genome instability is harmful, moderated genome instability can drive adaptation to novel environments by maximising genetic...

Full description

Bibliographic Details
Main Authors: Marzia Rizzo, Natthapon Soisangwan, Samuel Vega-Estevez, Robert Jordan Price, Chloe Uyl, Elise Iracane, Matt Shaw, Jan Soetaert, Anna Selmecki, Alessia Buscaino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010576

Internet

https://doi.org/10.1371/journal.pgen.1010576

Similar Items