Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation

Highlights M0 macrophages accounted for more than 9.8%, indicating a poor prognosis in pancreatic cancer. M0 macrophages proportion were negatively correlated with CD8 + T cells, and immune scores. M0 macrophages promote pancreatic cancer growth in vivo. Elimination of M0 macrophages may be a promis...

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Bibliographic Details
Main Authors: Pan-ling Xu, Chien-shan Cheng, Ting Wang, Shu Dong, Ping Li
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-10597-9