Knockout of THBS1 gene improves immune microenvironment of visceral fat and inhibits intraperitoneal implantation and metastasis of colorectal cancer in mice
Objective To investigate the effects of thrombospondin1 (THBS1) gene knockout on immune microenvironment and tumor progression of colorectal cancer. Methods THBS1 gene knockout (THBS1-/-) mice were constructed and its genotypes were determined by PCR and agarose gel electrophoresis. Subcutaneous tum...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Army Medical University
2023-09-01
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| Series: | 陆军军医大学学报 |
| Subjects: | |
| Online Access: | http://aammt.tmmu.edu.cn/html/202303119.ht |