Spliceosomal GTPase Eftud2 regulates microglial activation and polarization

Spliceosomal GTPase Eftud2 regulates microglial activation and polarization

Elongation factor Tu GTP binding domain protein 2 (Eftud2) is a spliceosomal GTPase that serves as an innate immune modulator restricting virus infection. Microglia are the resident innate immune cells and the key players of immune response in the central nervous system. However, the role of Eftud2...

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Bibliographic Details
Main Authors: Guo-Chao Yang, Yuan Shi, Chao-Nan Fan, Ying Li, Meng-Qi Yuan, Jie Pei, Yan Wu, Hai-Tao Wu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; anti-inflammatory phenotype; bv2; eftud2; inflammation; lipopolysaccharide; microglia; nuclear factor-kappab; proinflammatory phenotype; spliceosomal gtpase
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=4;spage=856;epage=862;aulast=Yang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=4;spage=856;epage=862;aulast=Yang

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