Genomic insights into host and parasite interactions during intracellular infection by Toxoplasma gondii

To gain insights into the molecular interactions of an intracellular pathogen and its host cell, we studied the gene expression and chromatin states of human fibroblasts infected with the Apicomplexan parasite Toxoplasma gondii. We show a striking activation of host cell genes that regulate a number...

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Bibliographic Details
Main Authors: Netha Ulahannan, Ronald Cutler, Reanna Doña-Termine, Claudia A. Simões-Pires, N. Ari Wijetunga, Matthew McKnight Croken, Andrew D. Johnston, Yu Kong, Shahina B. Maqbool, Masako Suzuki, John M. Greally
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524707/?tool=EBI