Ultraconserved Elements Occupy Specific Arenas of Three-Dimensional Mammalian Genome Organization

Summary: This study explores the relationship between three-dimensional genome organization and ultraconserved elements (UCEs), an enigmatic set of DNA elements that are perfectly conserved between the reference genomes of distantly related species. Examining both human and mouse genomes, we interro...

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Bibliographic Details
Main Authors: Ruth B. McCole, Jelena Erceg, Wren Saylor, Chao-ting Wu
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718309410