Use of humanised rat basophilic leukaemia cell line RS-ATL8 for the assessment of allergenicity of Schistosoma mansoni proteins.

Parasite-specific IgE is thought to correlate with protection against Schistosoma mansoni infection or re-infection. Only a few molecular targets of the IgE response in S. mansoni infection have been characterised. A better insight into the basic mechanisms of anti-parasite immunity could be gained...

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Main Authors: Daniel Wan, Fernanda Ludolf, Daniel G W Alanine, Owen Stretton, Eman Ali Ali, Nafal Al-Barwary, Xiaowei Wang, Michael J Doenhoff, Adriano Mari, Colin M Fitzsimmons, David W Dunne, Ryosuke Nakamura, Guilherme C Oliveira, Marcos J C Alcocer, Franco H Falcone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4177753?pdf=render