Measuring phenotype-phenotype similarity through the interactome

Abstract Background Recently, measuring phenotype similarity began to play an important role in disease diagnosis. Researchers have begun to pay attention to develop phenotype similarity measurement. However, existing methods ignore the interactions between phenotype-associated proteins, which may l...

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Bibliographic Details
Main Authors: Jiajie Peng, Weiwei Hui, Xuequn Shang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2102-9