Optogenetic regulation of endogenous proteins
Optogenetic approaches to control protein-protein interactions usually require overexpression of the target proteins. Here the authors integrate intrabodies into near-infrared- and blue-light activatable optogenetic tools to control endogenous proteins in mammalian cells.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14460-4 |