Antibacterial Activity of Isobavachalcone (IBC) Is Associated with Membrane Disruption

Antibacterial Activity of Isobavachalcone (IBC) Is Associated with Membrane Disruption

Isobavachalcone (<b>IBC</b>) is a natural prenylated chalcone with a broad spectrum of pharmacological properties. In this work, we newly synthesized and investigated the antibacterial activity of <b>IBC</b> against Gram-positive, Gram-negative and mycobacterial species. <...

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Bibliographic Details
Main Authors: Leticia Ribeiro de Assis, Reinaldo dos Santos Theodoro, Maria Beatriz Silva Costa, Julyanna Andrade Silva Nascentes, Miguel Divino da Rocha, Meliza Arantes de Souza Bessa, Ralciane de Paula Menezes, Guilherme Dilarri, Giovane Böerner Hypolito, Vanessa Rodrigues dos Santos, Cristiane Duque, Henrique Ferreira, Carlos Henrique Gomes Martins, Luis Octavio Regasini
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Membranes
Subjects:
chalcone
membrane
natural product
antibacterial
biofilm
Online Access:https://www.mdpi.com/2077-0375/12/3/269

Internet

https://www.mdpi.com/2077-0375/12/3/269

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