The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia

Summary: Microglia are the brain’s resident immune cells, performing surveillance to promote homeostasis and healthy functioning. While microglial chemical signaling is well-studied, mechanical cues regulating their function are less well-understood. Here, we investigate the role of the mechanosensi...

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Bibliographic Details
Main Authors: Ting Zhu, Jinghui Guo, Yong Wu, Ting Lei, Jiejun Zhu, Hui Chen, Shashwati Kala, Kin Fung Wong, Chi Pong Cheung, Xiaohui Huang, Xinyi Zhao, Minyi Yang, Lei Sun
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000706