A systematic review of interleukin-2-based immunotherapies in clinical trials for cancer and autoimmune diseasesResearch in context

Summary: Background: The cytokine interleukin-2 (IL-2) can stimulate both effector immune cells and regulatory T (Treg) cells. The ability of selectively engaging either of these effects has spurred interest in using IL-2 for immunotherapy of cancer and autoimmune diseases. Thus, numerous IL-2-base...

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Bibliographic Details
Main Authors: Miro E. Raeber, Dilara Sahin, Ufuk Karakus, Onur Boyman
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423001044