Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling

Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling

Diabetic cardiomyopathy (DCM) leads to heart failure and death in diabetic patients, no effective treatment is available. Notoginsenoside R1 (NGR1) is a novel saponin that is derived from Panax notoginseng and our previous studies have showed cardioprotective and neuroprotective effects of NGR1. How...

Full description

Bibliographic Details
Main Authors: Bin Zhang, Jingyi Zhang, Chenyang Zhang, Xuelian Zhang, Jingxue Ye, Shihuan Kuang, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
diabetes mellitus
diabetic cardiomyopathy
estrogen receptor
apoptosis
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01227/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01227/full

Similar Items