The Effect of Deuteration on the H<sub>2</sub> Receptor Histamine Binding Profile: A Computational Insight into Modified Hydrogen Bonding Interactions
We used a range of computational techniques to reveal an increased histamine affinity for its H<sub>2</sub> receptor upon deuteration, which was interpreted through altered hydrogen bonding interactions within the receptor and the aqueous environment preceding the binding. Molecular dock...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/24/6017 |