Three-Dimensional Genome Organization in Breast and Gynecological Cancers: How Chromatin Folding Influences Tumorigenic Transcriptional Programs

Three-Dimensional Genome Organization in Breast and Gynecological Cancers: How Chromatin Folding Influences Tumorigenic Transcriptional Programs

A growing body of research on the transcriptome and cancer genome has demonstrated that many gynecological tumor-specific gene mutations are located in cis-regulatory elements. Through chromosomal looping, cis-regulatory elements interact which each other to control gene expression by bringing dista...

Full description

Bibliographic Details
Main Authors: Stephanie I. Nuñez-Olvera, Jonathan Puente-Rivera, Rosalio Ramos-Payán, Carlos Pérez-Plasencia, Yarely M. Salinas-Vera, Lorena Aguilar-Arnal, César López-Camarillo
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
3D genome
cis-regulatory elements
topology-associated domains
CTCF
breast cancer
gynecological cancers
Online Access:https://www.mdpi.com/2073-4409/11/1/75

Internet

https://www.mdpi.com/2073-4409/11/1/75

Similar Items