Expert Consensus on Targeted Therapy of NSCLC with MET Exon 14 
Skipping Mutation

Expert Consensus on Targeted Therapy of NSCLC with MET Exon 14 
Skipping Mutation

The mesenchymal-epithelial transition factor (MET) exon 14 skipping mutation is mainly caused by the loss of c-Cbl tyrosine binding site. This mutation could result in a decrease in the degradation rate of proteasome-mediated MET proteins, trigger continuous activation of downstream pathways, and ul...

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Bibliographic Details
Main Author: Lung Cancer Specialty Committee of Chinese Elderly Health Care Association
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2023-06-01
Series:Chinese Journal of Lung Cancer
Subjects:
lung neoplasms
met exon 14 skipping mutation
met inhibitors
targeted therapy
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2023.102.19

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2023.102.19

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