Design, synthesis, docking and mechanistic studies of new thiazolyl/thiazolidinylpyrimidine-2,4-dione antiproliferative agents
In this article, we display on the synthesis and biological evaluation of a new series of thiazolylpyrimidine 3a-l and thiazolidinylpyrimidine derivatives 5a-e. The structures of the new compounds were confirmed by using different spectral techniques including NMR, IR, mass spectroscopy in addition...
Main Authors: | Ashraf A. Aly, Mohammed B. Alshammari, Akil Ahmad, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Stefan Bräse, Mahmoud A. A. Ibrahim, Asmaa H. Mohamed |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-04-01
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Series: | Arabian Journal of Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535223000734 |
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