The unusual gene architecture of polyubiquitin is created by dual-specific splice sites

Abstract Background The removal of introns occurs through the splicing of a 5′ splice site (5′ss) with a 3′ splice site (3′ss). These two elements are recognized by distinct components of the spliceosome. However, introns in higher eukaryotes contain many matches to the 5′ and 3′ splice-site motifs...

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Bibliographic Details
Main Authors: Chaorui Duan, Truman Mooney, Luke Buerer, Cory Bowers, Stephen Rong, Seong Won Kim, Alger M. Fredericks, Sean F. Monaghan, William G. Fairbrother
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-023-03157-8