Cobalt-Catalyzed Cyclization of 2-Bromobenzamides with Carbodiimides: A New Route for the Synthesis of 3-(Imino)isoindolin-1-ones

Cobalt-Catalyzed Cyclization of 2-Bromobenzamides with Carbodiimides: A New Route for the Synthesis of 3-(Imino)isoindolin-1-ones

A novel synthetic pathway to approach 3-(imino)isoindolin-1-ones by the Co-catalyzed cyclization reaction of 2-bromobenzamides with carbodiimides has been developed. This catalytic reaction can tolerate a variety of substituents and provide corresponding products in moderate yields for most cases. A...

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Bibliographic Details
Main Authors: Hasil Aman, Yu-Chiao Huang, Yu-Hao Liu, Yu-Lin Tsai, Min Kim, Jen-Chieh Hsieh, Gary Jing Chuang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
cobalt-catalyzed
<i>N</i>-heterocycle
cyclization
carbodiimide
3-(imino)isoindolin-1-one
Online Access:https://www.mdpi.com/1420-3049/26/23/7212

Internet

https://www.mdpi.com/1420-3049/26/23/7212

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