MEIRLOP: improving score-based motif enrichment by incorporating sequence bias covariates

MEIRLOP: improving score-based motif enrichment by incorporating sequence bias covariates

Abstract Background Motif enrichment analysis (MEA) identifies over-represented transcription factor binding (TF) motifs in the DNA sequence of regulatory regions, enabling researchers to infer which transcription factors can regulate transcriptional response to a stimulus, or identify sequence feat...

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Bibliographic Details
Main Authors: Nathaniel P. Delos Santos, Lorane Texari, Christopher Benner
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Bioinformatics
Subjects:
Motif enrichment
Logistic regression
Differential analysis
ChIP-seq
MEIRLOP
Score-based
Online Access:http://link.springer.com/article/10.1186/s12859-020-03739-4

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http://link.springer.com/article/10.1186/s12859-020-03739-4

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