Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis

Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis

Diphthamide is a post-translationally modified histidine residue present in animal and yeast TRANSLATION ELONGATION FACTOR2. Here the authors show that diphthamide modification of eEF2 is conserved in Arabidopsis thaliana and contributes to translational fidelity and growth via cell proliferation.

Bibliographic Details
Main Authors: Hongliang Zhang, Julia Quintana, Koray Ütkür, Lorenz Adrian, Harmen Hawer, Klaus Mayer, Xiaodi Gong, Leonardo Castanedo, Anna Schulten, Nadežda Janina, Marcus Peters, Markus Wirtz, Ulrich Brinkmann, Raffael Schaffrath, Ute Krämer
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31712-7

Internet

https://doi.org/10.1038/s41467-022-31712-7

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