Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis
Diphthamide is a post-translationally modified histidine residue present in animal and yeast TRANSLATION ELONGATION FACTOR2. Here the authors show that diphthamide modification of eEF2 is conserved in Arabidopsis thaliana and contributes to translational fidelity and growth via cell proliferation.
Bibliographic Details
Main Authors: |
Hongliang Zhang,
Julia Quintana,
Koray Ütkür,
Lorenz Adrian,
Harmen Hawer,
Klaus Mayer,
Xiaodi Gong,
Leonardo Castanedo,
Anna Schulten,
Nadežda Janina,
Marcus Peters,
Markus Wirtz,
Ulrich Brinkmann,
Raffael Schaffrath,
Ute Krämer |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2022-07-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-022-31712-7
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