Diterpenoids from <i>Plectranthus</i> spp. as Potential Chemotherapeutic Agents via Apoptosis

Diterpenoids from <i>Plectranthus</i> spp. as Potential Chemotherapeutic Agents via Apoptosis

<i>Plectranthus</i> spp. is widely known for its medicinal properties and bioactive metabolites. The cytotoxic and genotoxic properties of the four known abietane diterpenoids: 7α-Acetoxy-6β-hydroxyroyleanone (Roy), 6,7-dehydroroyleanone (Deroy), 7β,6β-dihydroxyroyleanone6 (Diroy), and P...

Full description

Bibliographic Details
Main Authors: Tomasz Śliwiński, Przemysław Sitarek, Ewa Skała, Vera M. S. Isca, Ewelina Synowiec, Tomasz Kowalczyk, Michał Bijak, Patrícia Rijo
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceuticals
Subjects:
<i>Plectranthus</i> sp.
cytotoxic activity
apoptosis
DNA damage
mitochondrial membrane potential
ROS levels
Online Access:https://www.mdpi.com/1424-8247/13/6/123

Internet

https://www.mdpi.com/1424-8247/13/6/123

Similar Items