A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet

A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet

Abstract Background Nonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have focused on reducing the intake of trans fatty acids (TFAs) because of potential hazards to human health and...

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Bibliographic Details
Main Authors: Noriko Suzuki-Kemuriyama, Akari Abe, Kiniko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Lipids in Health and Disease
Subjects:
Nonalcoholic steatohepatitis
Trans fatty acid substitutes
Choline-deficient
Methionine-lowered
L-amino acid-defined
High-fat diet
Online Access:https://doi.org/10.1186/s12944-020-01423-3

Internet

https://doi.org/10.1186/s12944-020-01423-3

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