Regulation of neutral sphingomyelinase-2 by GSH: a new insight to the role of oxidative stress in aging-associated inflammation

Oxidative stress and inflammation are fundamental for the onset of aging and appear to be causatively linked. Previously, we reported that hepatocytes from aged rats, compared with young rats, are hyperresponsive to interleukin-1β (IL-1β) stimulation and exhibit more potent c-Jun N-terminal kinase (...

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Bibliographic Details
Main Authors: Kristina Rutkute, Reto H. Asmis, Mariana N. Nikolova-Karakashian
Format: Article
Language:English
Published: Elsevier 2007-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520424435