ANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores
Abstract Macroautophagy is a process that cells engulf cytosolic materials by autophagosomes and deliver them to lysosomes for degradation. The biogenesis of autophagosomes requires ATG2 as a lipid transfer protein to transport lipids from existing membranes to phagophores. It is generally believed...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-04-01
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Series: | Cell Discovery |
Online Access: | https://doi.org/10.1038/s41421-024-00659-y |