ANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores

ANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores

Abstract Macroautophagy is a process that cells engulf cytosolic materials by autophagosomes and deliver them to lysosomes for degradation. The biogenesis of autophagosomes requires ATG2 as a lipid transfer protein to transport lipids from existing membranes to phagophores. It is generally believed...

Full description

Bibliographic Details
Main Authors: Bin Wei, Yuhui Fu, Xiuzhi Li, Fang Chen, Yiqing Zhang, Hanmo Chen, Mindan Tong, Linsen Li, Yi Pan, Shen Zhang, She Chen, Xiaoxia Liu, Qing Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2024-04-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-024-00659-y

Internet

https://doi.org/10.1038/s41421-024-00659-y

Similar Items