Catalysis of ACAT may be completed within the plane of the membrane: a working hypothesis
Two ACAT sharing protein sequence homology near their C termini have been identified. Both proteins may span the endoplasmic reticulum (ER) membrane several times. There is good evidence implicating the role of ACAT1 in macrophage foam cell formation, and ACAT2 in intestinal cholesterol absorption....
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2001-12-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520315212 |