Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes
Abstract Existing methods for paired antibody heavy- and light-chain repertoire sequencing rely on specialized equipment and are limited by their commercial availability and high costs. Here, we report a novel simple and cost-effective emulsion-based single-cell paired antibody repertoire sequencing...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | Genome Medicine |
Online Access: | http://link.springer.com/article/10.1186/s13073-018-0542-5 |