Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy

Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy

Nuclear factor erythroid 2-related factor 2 (NRF2), a redox sensor, is vital for cellular redox homeostasis. We reported that transgenic mice expressing constitutively active Nrf2 (CaNrf2-TG) exhibit reductive stress (RS). In this study, we identified novel protein signature for RS-induced cardiomyo...

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Bibliographic Details
Main Authors: Sini Sunny, Arun Jyothidasan, Cynthia L. David, Krishna Parsawar, Arul Veerappan, Dean P. Jones, Steven Pogwizd, Namakkal S. Rajasekaran
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
reductive stress
caNrf2
myocardial proteome
Tandem Mass Tag proteomic analysis
speckle tracking echocardiography
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.848045/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.848045/full

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