Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism

Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism

Abstract l-DOPA is deficient in the developing albino eye, resulting in abnormalities of retinal development and visual impairment. Ongoing retinal development after birth has also been demonstrated in the developing albino eye offering a potential therapeutic window in humans. To study whether huma...

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Bibliographic Details
Main Authors: Aida Sanchez-Bretano, Eloise Keeling, Jennifer A. Scott, Savannah A. Lynn, Sudha Priya Soundara-Pandi, Sarah L. Macdonald, Tutte Newall, Helen Griffiths, Andrew J. Lotery, J. Arjuna Ratnayaka, Jay E. Self, Helena Lee
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44373-3

Internet

https://doi.org/10.1038/s41598-023-44373-3

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