Discovery of 29-O-acyl-toosendanin-based derivatives as potent anti-cancer agents

Structural modification of natural products is an effective strategy to discover potent lead compounds with improved medicinal performance. Toosendanin (TSN), a natural limonoid with diverse pharmacological properties, was selected as the starting material for structural modification to obtain more...

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Bibliographic Details
Main Authors: Ming-Feng Zou, Run-Zhu Fan, Ai-Ping Yin, Rong Hu, Dong Huang, Wei Li, Sheng Yin, Rong Pu, Gui-Hua Tang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222005998