Breast carcinomas with low amplified/equivocal HER2 by Ish: potential supporting role of multiplex ligation-dependent probe amplification

Breast carcinomas with low amplified/equivocal HER2 by Ish: potential supporting role of multiplex ligation-dependent probe amplification

Abstract Background This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gen...

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Bibliographic Details
Main Authors: Cristiana Ercolani, Caterina Marchiò, Anna Di Benedetto, Alessandra Fabi, Letizia Perracchio, Patrizia Vici, Francesca Sperati, Simonetta Buglioni, Vincenzo Arena, Edoardo Pescarmona, Anna Sapino, Irene Terrenato, Marcella Mottolese
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Breast Cancer
HER2
Immunohistochemistry
In Situ Hybridization
MLPA
Online Access:http://link.springer.com/article/10.1186/s13046-017-0613-2

Internet

http://link.springer.com/article/10.1186/s13046-017-0613-2

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