Exploring the Diverse Functional and Regulatory Consequences of Alternative Splicing in Development and Disease

Exploring the Diverse Functional and Regulatory Consequences of Alternative Splicing in Development and Disease

Alternative splicing is a fundamental mechanism of eukaryotic RNA regulation that increases the transcriptomic and proteomic complexity within an organism. Moreover, alternative splicing provides a framework for generating unique yet complex tissue- and cell type-specific gene expression profiles, d...

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Bibliographic Details
Main Authors: M. Brandon Titus, Adeline W. Chang, Eugenia C. Olesnicky
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
alternative splicing
RNA localization
splicing factors
RNA binding proteins
poison exons
premature termination codon (PTC)
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.775395/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.775395/full

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