Linking Cancer Metabolic Dysfunction and Genetic Instability through the Lens of Iron Metabolism

Iron (Fe) is an essential element that plays a fundamental role in a wide range of cellular functions, including cellular proliferation, DNA synthesis, as well as DNA damage and repair. Because of these connections, iron has been strongly implicated in cancer development. Cancer cells frequently hav...

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Bibliographic Details
Main Authors: Michael S. Petronek, Douglas R. Spitz, Garry R. Buettner, Bryan G. Allen
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1077