High-Frequency Deep Brain Stimulation of the Substantia Nigra Pars Reticulata Facilitates Extinction and Prevents Reinstatement of Methamphetamine-Induced Conditioned Place Preference

High-Frequency Deep Brain Stimulation of the Substantia Nigra Pars Reticulata Facilitates Extinction and Prevents Reinstatement of Methamphetamine-Induced Conditioned Place Preference

Persistent and stable drug memories lead to a high rate of relapse among addicts. A number of studies have found that intervention in addiction-related memories can effectively prevent relapse. Deep brain stimulation (DBS) exhibits distinct therapeutic effects and advantages in the treatment of neur...

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Bibliographic Details
Main Authors: Libo Zhang, Shiqiu Meng, Wenjun Chen, Yun Chen, Enze Huang, Guipeng Zhang, Yisen Liang, Zengbo Ding, Yanxue Xue, Jie Shi, Yu Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
deep brain stimulation
substantia nigra pars reticulata
methamphetamine
extinction
relapse
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.705813/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.705813/full

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