A New Method to Stabilize c-kit Expression in Reparative Cardiac Mesenchymal Cells

A New Method to Stabilize c-kit Expression in Reparative Cardiac Mesenchymal Cells

Cell therapy improves cardiac function. Few cells have been investigated more extensively or consistently shown to be more effective than c-kit sorted cells; however, c-kit expression is easily lost during passage. Here, our primary goal was to develop an improved method to isolate c-kitpos cells an...

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Bibliographic Details
Main Authors: Marcin Wysoczynski, Sujith Dassanayaka, Ayesha Zafir, Shahab Ghafghazi, Bethany W Long, Camille Noble, Angelica DeMartino, Kenneth R Brittian, Roberto Bolli, Steven P Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Heart Failure
cell therapy
c-kit
Myocardial repair
Mesenchymal cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00078/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00078/full

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