Comparative Effects of Di-(2-ethylhexyl)phthalate and Di-(2-ethylhexyl)terephthalate Metabolites on Thyroid Receptors: In Vitro and In Silico Studies

Comparative Effects of Di-(2-ethylhexyl)phthalate and Di-(2-ethylhexyl)terephthalate Metabolites on Thyroid Receptors: In Vitro and In Silico Studies

Plasticizers added to polyvinylchloride (PVC) used in medical devices can be released into patients’ biological fluids. Di-(2-ethylhexyl)phthalate (DEHP), a well-known reprotoxic and endocrine disruptor, must be replaced by alternative compounds. Di-(2-ethylhexyl) terephthalate (DEHT) is an interest...

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Bibliographic Details
Main Authors: Nicolas Kambia, Isabelle Séverin, Amaury Farce, Laurence Dahbi, Thierry Dine, Emmanuel Moreau, Valérie Sautou, Marie-Christine Chagnon
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Metabolites
Subjects:
DEHT
in silico
T-screen assay
hormonal activities
thyroid receptors
Online Access:https://www.mdpi.com/2218-1989/11/2/94

Internet

https://www.mdpi.com/2218-1989/11/2/94

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