Glycation and a Spark of ALEs (Advanced Lipoxidation End Products) – Igniting RAGE/Diaphanous-1 and Cardiometabolic Disease

Glycation and a Spark of ALEs (Advanced Lipoxidation End Products) – Igniting RAGE/Diaphanous-1 and Cardiometabolic Disease

Obesity and non-alcoholic fatty liver disease (NAFLD) are on the rise world-wide; despite fervent advocacy for healthier diets and enhanced physical activity, these disorders persist unabated and, long-term, are major causes of morbidity and mortality. Numerous fundamental biochemical and molecular...

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Bibliographic Details
Main Authors: Lakshmi Arivazhagan, Raquel López-Díez, Alexander Shekhtman, Ravichandran Ramasamy, Ann Marie Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
RAGE axis
glycation
lipoxidation
cardiometabolic disease
obesity
non-alcoholic fatty liver disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.937071/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.937071/full

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