A deeper look at carrier proteome effects for single-cell proteomics

Ye et al. address a highly debated aspect of many recent single cell proteomics studies, the extent and impact of the carrier proteome. Through deployment of a mixed-species sample at various spike-in levels, they set up an experimental system for further exploration of the carrier effects on TMT-ba...

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Bibliographic Details
Main Authors: Zilu Ye, Tanveer S. Batth, Patrick Rüther, Jesper V. Olsen
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03095-4