Hyperphosphorylation of Tau Protein in Hippocampus of Central Insulin-Resistant Rats is Associated with Cognitive Impairment

Hyperphosphorylation of Tau Protein in Hippocampus of Central Insulin-Resistant Rats is Associated with Cognitive Impairment

Background: Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Peripheral insulin resistance increases the risk for memory impairment and the development of AD. Objective: This study aims to assess changes in cognitive functions and the level of hyperphosphorylated t...

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Bibliographic Details
Main Authors: Dantao Peng, Xiuqing Pan, Ju Cui, Yueqin Ren, Jiewen Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Insulin resistance
Streptozotocin
Hyperphosphorylation
Tau protein
Alzheimer's disease
Online Access:http://www.karger.com/Article/FullText/356579

Internet

http://www.karger.com/Article/FullText/356579

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